Intestinal malabsorption in cystic fibrosis.

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Intestinal malabsorption in cystic fibrosis.

An oral solution containing lactulose and L-rhamnose was administered to six patients with cystic fibrosis. Intestinal absorption of both sugars was assessed by measurement of their urinary excretion. The lactulose: L-rhamnose excretion ratio was raised, supporting the hypothesis of an intestinal component to the malabsorption of cystic fibrosis.

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This study aimed at examining the mechanisms participating in excessive faecal bile acid loss in cystic fibrosis. The study was designed to define the relation between faecal fat and faecal bile acid loss in patients with and without cystic fibrosis related liver disease; to assess terminal ileal bile acid absorption by a seven day whole body retention of selenium labelled homotaurocholic acid ...

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Intestinal inflammation in cystic fibrosis.

BACKGROUND There is controversy about whether the inflammatory response observed in the cystic fibrosis (CF) lung occurs secondary to bacterial infection or is caused by a dysregulation of the inflammatory response associated with the basic cellular defect of CF. AIMS To study the inflammatory response in the gastrointestinal tract of children with CF; and to investigate whether there is incr...

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Effect of misoprostol on fat malabsorption in cystic fibrosis.

Misoprostol, a synthetic prostaglandin that is known to reduce gastric acid production and stimulate duodenal bicarbonate production, was evaluated in 22 patients with cystic fibrosis. In those patients who had greater than 10% fat malabsorption while taking pancrease the addition of misoprostol significantly reduced the degree of fat malabsorption.

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1986

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.61.11.1127